1. by lacing placebos with substances that have similar reactions to test material.
(often used aspartame, a structural analogue of MSG).
2. by allowing study participants to eat food or drink liquids that might contain allergens.
3. by scheduling test treatment first and placebo treatment second, then it would be possible to account late occurring test material reactions to placebos.
4. providing meals to each participant, increasing chances of food sensitivity.
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