1. 2 mg per gram body weight dose of MSG was administered subcutaneously to new born mice perinatally and every other day thereafter till day 10. Increased number of primary ovarian follicles without increase in Graafian follicle number observed. (Graafian follicles contain mature egg of females). (Das R.S. Ghosh S.K., 2011)
2. When MSG was given at .04 mg/kg or .08 mg/kg daily oral dose to female rats, a number of pathological changes could be observed in their ovarian tissues. These ovarian changes include cellular hypertrophy in theca follicles, destruction of basement membranes and stroma cell vacuolations. In addition, changes in Fallopian tubes were also reported. Separation of endosalphinx from myosalphinx and presence of stroma cells with vacuolations or lysed red blood cells were among major cellular destructions. (Eweka A.O. et. al., 2010) (Eweka A.O. et. al., 2011)
As human females carry high numbers of glutamate receptors on uterus, Fallopian tubes and ovarian follicles, under mentioned evidence links modern world MSG over consumption with increasing occurrence of female sub-fertility and miscarriages.
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