GUT MICROBIOME CONTROLS YOUR TOXIN EXPOSURE

Prebiotics intake can help in microbial fermentation of your gut, with additional benefits of appetite reduction through rise in GLP-1 / Neuropeptide Y levels  improved post prandial glucose responses and improved leptin sensitivity, researchers say. The data comes from randomized, double blind, placebo control trial that administered 16 grams of prebiotics versus 16 grams of dextrin / maltose to two groups. Further, gut microbiome has the unique ability to modulate intestinal endocannabinoid system tone that is known to control gut permeability. As dangerous lipopolysaccharides produced by Gram negative bacteria can leak into blood stream in the presence of highly permeable gut, prebiotics are very important as a preventive measure.

You don't need supplements - best prebiotic foods include garlic, onion, asparagus, banana, barley, oats, apples, cocoa, wheat bran, leeks and flaxseeds.

P. D. Cani, E. Lecourt, E. M. Dewulf et al., “Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal,” American Journal of Clinical Nutrition, vol. 90, no. 5, pp. 1236–1243, 2009.

A. Everard, V. Lazarevic, M. Derrien et al., “Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice,” Diabetes, vol. 60, no. 11, pp. 2775–2786, 2011.

G. G. Muccioli, D. Naslain, F. Bäckhed et al., “The endocannabinoid system links gut microbiota to adipogenesis,” Molecular Systems Biology, vol. 6, article 392, 2010.