All processed
free glutamic acid (MSG), no matter how produced, is accompanied by unwanted
by-products of production. These unwanted by-products of production are
referred to as impurities. Impurities are invariably produced by all
methods used for breaking down protein (autolysis, enzymolysis, and acid
hydrolysis)(4,8-12), by all methods used to produce monosodium glutamate(7), and by all methods use to produce reaction or
processed flavors (5,13).
When acid hydrolysis is used to
free amino acids from protein, the impurities produced included carcinogenic
mono and dichloro propanols(4,12). Reaction
flavors produced through a maillard reaction may contain carcinogenic
heterocyclic amines(13).
1. Dichloro propanols (1,3-DCP) ; Cancer potential
Statistically significant dose-related increases in the combined incidences of the following tumors were observed in male and female rats: in the liver, hepatocellular adenoma and carcinoma; in the tongue/oral cavity, squamous cell papilloma and carcinoma; and in the thyroid, follicular cell adenoma and carcinoma. In the kidney, the combined numbers of renal tubular adenoma and carcinoma were increased in males only. In numerous in vitro assays, 1,3-DCP was genotoxic.
2. Heterocyclic amines are linked to;
- Colorectal cancer
- Breast cancer
- Prostate cancer
- Pancreatic cancer
(TLC)
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